BDBM50157842 3-Hydroxy-5-methyl-4a,7a-dihydro-1H-thieno[2,3-d]pyrimidine-2,4-dione::CHEMBL183792

SMILES Cc1csc2[nH]c(=O)n(O)c(=O)c12

InChI Key InChIKey=VCPLNXWOFQOPTD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157842   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50157842(3-Hydroxy-5-methyl-4a,7a-dihydro-1H-thieno[2,3-d]p...)
Affinity DataIC50:  100nMAssay Description:Inhibition of RNH activity of recombinant HIV1 reverse transcriptase RNase H assessed as reduction in internal cleavage of RNA strand using RNA/DNA d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed